![]() ![]() The WHO also notes that while this vaccine has not been sufficiently tested in pregnant people, its similarity to other vaccines deemed safe, such as those for hepatitis B, suggests that there are no expected concerns for the use of the vaccine during pregnancy. It states that while the trials reviewed by SAGE did not include this specific population, CoronaVac is a nonreplicating vaccine and can be recommended. The WHO also recommends CoronaVac for people living with HIV. Similar to other COVID-19 vaccines approved by WHO, the global health agency recommends the CoronaVac vaccine for people with comorbidities, those who are immunocompromised, or those who previously have had COVID-19. It uses a dead version of the SARS-CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body’s immune system to create antibodies for protection against the live virus, if it were to invade. The Strategic Advisory Group of Experts on Immunization (SAGE), WHO’s main advisory board regarding vaccines, also reviewed the vaccine as part of WHO’s EUL validation.Īs of January 2022, the vaccine is approved for use in 52 countries.ĬoronaVac is an inactivated vaccine. WHO’s EUL procedure for CoronaVac included a review of the vaccine’s safety and efficacy, as well as “onsite inspections of the production facility.” Sinovac’s vaccine was validated for Emergency Use Listing (EUL) by the WHO on June 1. It has an efficacy rate of 50.4% for preventing symptomatic infection, according to data from a Brazilian trial, and an effectiveness of 67%, according to a real-world study in Chile. This two-dose vaccine is recommended for individuals aged 18 years and above. The company focuses specifically on the development and manufacturing of vaccines to target human infectious diseases. CoronaVac is a COVID-19 vaccine produced by Sinovac Biotech, a China-based pharmaceutical company with headquarters in Beijing.
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